CD206-PE, human 30 tests
货号:
130-099-732 基本售价:
询价 规格:
30 tests
产品信息
概述货号 | 130-099-732 |
描述 | The mannose receptor (MR), also known as macrophage MR or CD206, is a 162–175 kDa type I membrane protein. It contains an N-terminal cystein-rich domain and eight C-type lectin-like domains (CTLDs), beside a transmembrane and a cytoplasmic domain. CD206 is expressed by macrophages, dendritic cells, and subsets of endothelial cells, but not on monocytes. The MR recognizes multiple mainly microbial carbohydrates with mannose, fucose, or N-acetyl glucosamine residues. The MR mediates endocytosis and phagocytosis, linked to antigen presentation. It plays an important role in host defense and provides a link between innate and adaptive immunity. |
别名 | MRC1, CLEC13D, CLEC13DL, MMR, MRC1L1 |
克隆号 | DCN228 |
同种亚型 | mouse IgG1κ |