CD324-PE (E-Cadherin), human 30 tests
货号：
130-099-688 基本售价：
询价 规格：
30 tests
产品信息
概述| 货号 | 130-099-688 |
| 描述 | CD324, also known as E-Cadherin or cadherin-1, is a calcium dependent cell adhesion protein found in adherence junctions of epithelial cells, e.g., in colon, uterus, liver, keratinocytes etc. E-Cadherin also serves as a ligand for integrin alpha-E/beta-71. The epitope is expressed by a variety of carcinoma-derived cell lines such as MCF-7, HT-29, T-47D, NTERA-2, and 2102Ep. Loss of E-Cadherin is thought to enable metastasis by disrupting intercellular contacts—an early step in metastatic dissemination2. Furthermore, E-Cadherin is a marker of undifferentiated embryonic stem (ES) cells and induced pluripotent stem (iPS) cells3,4. For these cells, E-Cadherin plays a major role in conveying cell survival signals5. |
| 别名 | CDH1, Arc-1, CDHE, ECAD, LCAM, UVO, E-Cadherin |
| 克隆号 | 67A4 |
| 同种亚型 | mouse IgG1κ |
