CD49d-PE, human 30 tests
货号：
130-099-691 基本售价：
询价 规格：
30 tests
产品信息
概述| 货号 | 130-099-691 |
| 描述 | CD49d, also known as the α4 integrin chain or VLA-4α chain, is a 150 kDa cell adhesion protein that is directly involved in mononuclear leukocyte trafficking. Dimerized with β7 integrin, the resulting α4β7 integrin binds VCAM-1 (CD106), MAdCAM-1, and fibronectin to facilitate the rolling of leukocytes along vascular epithelium. In T cells, on ligation of MAdCAM-1, α4β7 integrin also provides costimulation of T cell receptor/CD3–mediated signaling.CD49d is expressed on most mononuclear leukocytes, both in circulation or in lymphoid or other tissues, as well as on eosinophils and basophils. |
| 别名 | ITGA4, IA4, VLA-4α |
| 克隆号 | MZ18-24A9 |
| 同种亚型 | mouse IgG2bκ |
