CD146-PE, human 30 tests
货号：
130-097-939 基本售价：
询价 规格：
30 tests
产品信息
概述| 货号 | 130-097-939 |
| 描述 | Clone 541-10B2 recognizes the human CD146 antigen, also known as MUC18, MCAM, Mel‑CAM, and S-Endo-1. CD146 is a transmembrane glycoprotein belonging to the immunoglobulin superfamily and contains five extracellular immunoglobulin (Ig)-like domains.1,2 CD146 possesses a limited tissue expression distribution, including endothelial cells, pericytes, smooth muscle cells, follicular dendritic cells, melanoma cells, and a sub-population of activated T lymphocytes.1,3 CD146 is also expressed on marrow stromal cells (MSCs).4CD146 functions as a Ca2+-independent cell adhesion molecule that is involved in heterophilic cell-cell interactions5, and may be involved in the extravasion and/or homing of activated T cells.3 CD146 expression in melanoma is also directly associated with tumor growth and metastasis.6,7 |
| 别名 | MCAM, MUC18, Endo-CAM, Mel-CAM, S-endo |
| 克隆号 | 541-10B2 |
| 同种亚型 | mouse IgG1κ |
