CD284-PE, human 30 tests
货号：
130-100-378 基本售价：
询价 规格：
30 tests
产品信息
概述| 货号 | 130-100-378 |
| 描述 | Clone HTA125 reacts with CD284, a type I transmembrane signaling receptor, also known as Toll-like receptor 4 (TLR4). Toll-like receptors are a family of pattern recognition receptors detecting the presence and characteristics of an infection and induce appropriately tailored innate and adaptive immune responses. TLR4 associates with its coreceptor MD-2. Together with the lipopolysaccharide (LPS)-binding protein (LBP) and CD14, this complex is responsible for signaling upon LPS recognition. TLR4 is expressed on monocytes and myeloid dendritic cells. Low levels are expressed on B cells and granulocytes in human peripheral blood. HTA125 is able to block LPS-induced signaling and recognizes predominantly human TLR4 associated with MD-2. |
| 别名 | TLR4, ARMD10, TLR-4, TOLL |
| 克隆号 | HTA125 |
| 同种亚型 | mouse IgG2aκ |
