CD85d (ILT4)-PE, human 30 tests
货号：
130-100-567 基本售价：
询价 规格：
30 tests
产品信息
概述| 货号 | 130-100-567 |
| 描述 | Clone REA184 recognizes CD85d, also known as immunoglobulin-like transcript 4 (ILT4), leukocyte Ig-like receptor 2 (LIR2). CD85d is an inhibitory immunoreceptor, expressed mainly on myelomonocytic lineage cells.ILT4 has four tandem Ig-like extracellular domains and three immunoreceptor tyrosine-based inhibitory receptor motifs in its cytoplasmic tails, which recruit the tyrosine phosphatase SHP-1 (Src homology 2 domain containing phosphatase 1). ILT4 have been shown to interact with HLA-A, -B, -G1, and E molecules as ligands. HLA-G expression is restricted to trophoblasts and thus interaction of ILT4 with HLA-G is suggested to inhibit placental leukocytes, contributing to maternal tolerance of the fetal semiallograft. Additional Information: Clone REA184 displays negligible binding to Fc receptors. |
| 别名 | LILRB2, ILT-4, LIR2, MIR-10 |
| 克隆号 | REA184 |
| 同种亚型 | recombinant human IgG1 |
