CD302 (CLEC13A)-PE, human 30 tests
货号：
130-107-849 基本售价：
询价 规格：
30 tests
产品信息
概述| 货号 | 130-107-849 |
| 描述 | Clone REA509 recognizes the human CD302 antigen, a single-pass type I membrane protein, which is also known as C-type lectin domain family 13 member A (CLEC13A) or DCL-1. The C-type lectin superfamily is a large group of proteins which are characterized by the presence of one or more C-type lectin-like domains (CTLDs). The superfamily is divided into 17 groups based on their phylogeny and domain organisation. Despite the presence of a highly conserved domain, C-type lectins are functionally diverse and have been implicated in various processes including cell adhesion, tissue integration and remodelling, platelet activation, complement activation, pathogen recognition, endocytosis, and phagocytosis. CD302 was identified as a genetic fusion partner of human CD205 (DEC-205) in Hodgkins lymphoma cell lines and is classified as a group XV C-type lectin. The receptor consists of a single extracellular CTLD, a short spacer followed by a transmembrane region, and a cytoplasmic tail containing a putative tyrosine-based internalisation motif. Human CD302 is expressed on monocytes, macrophages, granulocytes, and dendritic cells.Additional information: Clone REA509 displays negligible binding to Fc receptors. |
| 别名 | BIMLEC, CLEC13A, DCL1, KIAA0022 |
| 克隆号 | REA509 |
| 同种亚型 | recombinant human IgG1 |
