CD202b (TIE-2)-PE, human 30 tests
货号：
130-101-606 基本售价：
询价 规格：
30 tests
产品信息
概述| 货号 | 130-101-606 |
| 描述 | Clone REA198 recognizes CD202b, which is 145 kDa type I transmembrane tyrosine kinase receptor. CD202b is composed of an amino-terminal ligand binding domain with immunoglobulin domains, epithelial growth factor repeats, and fibronectin-like 3 repeats, a single transmembrane domain, and an intracellular tyrosine kinase domain. Expression of CD202b is found on endothelial cells and a subpopulation of monocytes. Angiopoietins are the natural ligands of CD202b and activation of CD202b dependent signaling pathways are involved in survival and apoptosis of endothelial cells, in controlling vascular permeability, and regulation of the capillary sprouting that occurs during normal angiogenesis. Additional information: Clone REA198 displays negligible binding to Fc receptors. |
| 别名 | TEK, TIE-2, VMCM, VMCM1 |
| 克隆号 | REA198 |
| 同种亚型 | recombinant human IgG1 |
