CD166-PE, human 30tests
货号：
130-106-618 基本售价：
询价 规格：
30tests
产品信息
概述| 货号 | 130-106-618 |
| 描述 | Clone REA442 recognizes the human CD166 antigen, a single-pass type I membrane protein also known as activated leukocyte cell adhesion molecule (ALCAM). CD166, a member of the immunoglobulin superfamily and a ligand for the lymphocyte antigen CD6, mediates homophilic and heterophilic adhesion. It is expressed on activated leukocytes T cells, B cells, monocytes, hematopoietic stem cells (HSCs), metastasizing melanoma, neuronal cells, endothelial cells, hematopoiesis-supporting osteoblastic cell lines, and MSCs. CD166 expression is pathologically correlated with aggressive disease in a variety of cancers including melanoma, prostate, breast, ovarian, esophageal, and bladder cancers. It is also a universal functional marker of murine and human hematopoietic stem cells (HSC) and osteoblasts within the hematopoietic niche and it is involved in modulating HSC-niche interactions and HSC fate. Additional information: Clone REA442 displays negligible binding to Fc receptors. |
| 别名 | ALCAM, MEMD, MEMD |
| 克隆号 | REA442 |
| 同种亚型 | recombinant human IgG1 |
