Anti-Siglec-10-PE, human 30 tests
货号：
130-103-730 基本售价：
询价 规格：
30 tests
产品信息
概述| 货号 | 130-103-730 |
| 描述 | Clone 5G6 recognizes the sialic acid-binding Ig-like lectin 10 (Siglec-10) antigen, a member of the CD33-related group of siglecs. The cytoplasmic tail of Siglec-10 contains four tyrosines, two of which are embedded in ITIM-signaling motifs and are likely to be involved in intracellular signaling. Amongst peripheral blood leucocytes, Siglec-10 was found to be expressed on eosinophils, monocytes, and B cells. Higher levels of Siglec-10 were found on a minor subset of NK-like cells that express the CD16 low-affinity Fc receptor but lack the CD56 antigen. The molecular properties and expression pattern suggest that Siglec-10 may have evolved to function as an inhibitory receptor of the innate immune system. |
| 别名 | PRO940, SLG2, Siglec10, Siglec-like protein 2 (SLG2) |
| 克隆号 | 5G6 |
| 同种亚型 | mouse IgG1κ |
