Anti-IRF-7 (pS477/pS479)-PE, h 30 tests
货号：
130-104-749 基本售价：
询价 规格：
30 tests
产品信息
概述| 货号 | 130-104-749 |
| 描述 | Clone REA310 recognizes the interferon regulatory factor 7 (IRF-7) phosphorylated at serines 477 and 479 (pS477/pS479). IRF-7 is a member of the IRF family of transcription factors and a key player in the innate immune response against viral infections. Constitutive expression of IRF-7 is limited to peripheral blood lymphocytes and dendritic cells while in most cell types its expression can be induced by type I interferon. IRF-7 is sequestered in the cytoplasm of uninfected cells and following viral infection, double-stranded RNA, or toll-like receptor signaling, it becomes phosphorylated by TBK and IKK-i kinases. Phosphorylated IRF-7 migrates in the nucleus where it can activate interferon type I genes and other interferon-stimulated genes.Additional information: Clone REA310 displays negligible binding to Fc receptors. |
| 别名 | IRF7, IMD39, IRF-7H, IRF7A, IRF7B, IRF7C |
| 克隆号 | REA310 |
| 同种亚型 | recombinant human IgG1 |
