Anti-FoxA2-PE, human 30 tests
货号：
130-107-826 基本售价：
询价 规格：
30 tests
产品信息
概述| 货号 | 130-107-826 |
| 描述 | Clone REA506 recognizes the human forkhead box A2 (FoxA2) antigen, a transcription factor which is also known as hepatocyte nuclear factor 3β (HNF-3β). FoxA2 is involved in embryonic development, establishment of tissue-specific gene expression, and regulation of gene expression in differentiated tissues. It is thought to act as a pioneer factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. In embryonic development, FoxA2 is required for notochord formation. It is involved in the development of multiple endoderm-derived organ systems such as the liver, pancreas, and lungs. FoxA2 is also involved in glucose homeostasis. It regulates the expression of genes important for glucose sensing in pancreatic beta-cells and glucose homeostasis.Additional information: Clone REA506 displays negligible binding to Fc receptors. |
| 别名 | HNF3B, HNF-3B, TCF-3B, TCF-3B, HNF-3β |
| 克隆号 | REA506 |
| 同种亚型 | recombinant human IgG1 |
