Anti-MCP-1 (CCL2)-PE, human 30 tests
货号：
130-101-674 基本售价：
询价 规格：
30 tests
产品信息
概述| 货号 | 130-101-674 |
| 描述 | Clone REA248 recognizes the Monocyte chemotactic protein 1 (MCP-1) antigen, a member of the beta (C-C) chemokine subfamily, which is also known as C-C motif chemokine 2 (CCL2) or monocyte chemotactic and activating factor (MCAF). MCP-1 is anchored in the plasma membrane of endothelial cells and is primarily secreted by monocytes, macrophages and dendritic cells. Platelet derived growth factor is a major inducer of the MCP-1 gene. MCP-1 recruits monocytes, memory T cells, and dendritic cells to the sites of inflammation produced by either tissue injury or infection. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis.Additional Information: Clone REA248 displays negligible binding to Fc receptors. |
| 别名 | GDCF-2, HC11, HSMCR30, MCAF, MCP-1, Scya2, SMC-CF |
| 克隆号 | REA248 |
| 同种亚型 | recombinant human IgG1 |
