CD304 (BDCA-4/Neuropilin-1)p,h
货号：
130-090-693 基本售价：
询价 规格：
EA
产品信息
概述| 货号 | 130-090-693 |
| 描述 | Clone AD5-17F6 recognizes the human CD304 (BDCA-4) antigen. Like CD303 (BDCA-2), the CD304 (BDCA-4) antigen1 is specifically expressed on human plasmacytoid dendritic cells in blood1–3 and bone marrow4. Unlike CD303 (BDCA-2), expression of CD304 (BDCA-4) is up-regulated on plasmacytoid dendritic cells and induced on myeloid cells upon culturing.4 In inflamed tonsils, CD304 (BDCA-4) expression, apart from plasmacytoid dendritic cells, is also detected primarily on follicular B helper memory T cells.4 CD304 (BDCA-4) is identical to neuropilin-1 (NP-1),4 a neuronal receptor, which is known to be expressed on numerous nonhematopoietic cell types, including neurons, endothelial, and tumor cells. CD1a+ dendritic cells generated ex vivo from monocytes or hematopoietic precursor cells are CD304 (BDCA-4)+ but CD303 (BDCA-2)–.1 |
| 别名 | NRP1, BDCA-4, NP1, Nrp, VEGF165R |
| 克隆号 | AD5-17F6 |
| 同种亚型 | mouse IgG1 |
