CD137-Biotin, human 30 tests
货号：
130-110-899 基本售价：
询价 规格：
30 tests
产品信息
概述| 货号 | 130-110-899 |
| 描述 | Clone REA765 recognizes the human CD137 antigen, a 30 kDa glycoprotein of the tumor necrosis factor (TNF) receptor superfamily, a group of cytokines that can cause cell death (apoptosis). CD137 is mainly expressed on activated CD4+ and CD8+ T cells, activated B cells, and natural killer cells, but can also be found on resting monocytes and dendritic cells. As a costimulatory molecule it is involved in the activation and survival of CD4+ or CD8+ T cells and NK cells. CD137 has been described to be a suitable marker for antigen-specific activation of human CD8+ T cells, as it is not expressed on resting CD8+ T cells and its expression is reliably induced after 24 hours of stimulation.Additional information: Clone REA765 displays negligible binding to Fc receptors. |
| 别名 | CDw137, TNFRSF9, ILA, Ly-63, 4-1BB |
| 克隆号 | REA765 |
| 同种亚型 | recombinant human IgG1 |
