CD49e-Biotin, human 30 tests
货号：
130-110-589 基本售价：
询价 规格：
30 tests
产品信息
概述| 货号 | 130-110-589 |
| 描述 | Clone REA686 recognizes the human CD49e antigen, also known as integrin α5 chain. Integrins are cell-surface receptors, expressed as heterodimers essential in various processes mediating intercellular or cellmatrix interaction. Integrin α5 is composed of a heavy and a light chain linked by a disulfide bond. CD49e associates non-covalently with the integrin ß1 (CD29) forming the very late activation antigen-5 (VLA5) complex which is expressed on many cell types including peripheral lymphocytes, monocytes, fibroblasts, and endothelial cells and is a receptor for fibronectin and fibrinogen but functions also as a receptor for laminin and several other extracellular matrix proteins.Additional information: Clone REA686 displays negligible binding to Fc receptors. |
| 别名 | VLA-5α, α5 integrin, VLA-5, Integrin alpha-5 |
| 克隆号 | REA686 |
| 同种亚型 | recombinant human IgG1 |
