CD39-Biotin, human 30 tests
货号：
130-110-787 基本售价：
询价 规格：
EA
产品信息
概述| 货号 | 130-110-787 |
| 描述 | Clone REA739 recognizes the 70–100 kDa membrane-bound human CD39 molecule, which is expressed on an effector/memory-like subset of FoxP3+ regulatory T cells. CD39 is an ectonucleotidase and catalyzes the hydrolysis of extracellular nucleotides, for example, ATP. Together with CD73, which is an ecto-5’-nucleotidase, this can lead to the production of adenosine. High extracellular ATP concentrations indicate tissue injury and cell death and induce various pro-inflammatory responses in immune cells. Through its enzymatic activity, CD39 can contribute to the suppressive function of regulatory T cells, for example, by eliminating extracellular ATP or by generating adenosine, which has suppressive effects on various immune cells.Additional information: Clone REA739 displays negligible binding to Fc receptors. |
| 别名 | Entpd1, ATPDase, NTPDase-1, SPG64, EC3.6.1.5, gp80 |
| 克隆号 | REA739 |
| 同种亚型 | recombinant human IgG1 |
