CD8b-FITC, human 30 tests
货号：
130-110-567 基本售价：
询价 规格：
EA
产品信息
概述| 货号 | 130-110-567 |
| 描述 | Clone REA715 recognizes the human CD8b antigen, a single-pass type I membrane protein and member of the immunoglobulin superfamily, also known as T cell surface glycoprotein Lyt-3. The CD8 glycoprotein is expressed by thymocytes, mature T cells, and natural killer (NK) cells and has been implicated in the recognition of monomorphic determinants on major histocompatibility complex class I antigens and in signal transduction during the course of T cell activation. Both human and rodent CD8 antigens are comprised of two distinct polypeptide chains, alpha and beta. Most of peripheral blood CD8+ T lymphocytes express the CD8a/CD8b heterodimer, while CD8+CD16+ natural killer cells and CD8+ T cell receptor γ/δ+ T lymphocytes express only the CD8a/CD8a homodimer. CD8b can therefore be used to selectively bind to CD8+ T cells while excluding CD8+ NK cells.Additional information: Clone REA715 displays negligible binding to Fc receptors. |
| 别名 | CD8 beta chain, CD8 b chain, CD8b |
| 克隆号 | REA715 |
| 同种亚型 | recombinant human IgG1 |
