CD192 (CCR2)-Biotin, human 30 tests
货号：
130-109-653 基本售价：
询价 规格：
30 tests
产品信息
概述| 货号 | 130-109-653 |
| 描述 | Clone REA624 recognizes the CD192 antigen, a G protein–linked seven transmembrane receptor, which is also known as C-C chemokine receptor type 2 (CCR2) or monocyte chemoattractant protein 1 receptor (MCP-1-R). Two spliced variants of CD192 (CD192A and CD192B) are expressed on peripheral monocytes and basophils as a result of alternate splicing of a single gene and differ at the C-terminal end. CD192 and its main ligand CCL2 have been implicated in a wide range of immunobiological processes and neuropathologies, including recruitment of monocytes and regulation of bone marrow homeostasis, as well as multiple sclerosis, HIV-associated dementia, Alzheimer’s disease, and neuropathic pain. Additional information: Clone REA624 displays negligible binding to Fc receptors. |
| 别名 | C-C chemokine receptor type 2, C-C CKR-2, CC-CKR-2, CCR-2, Monocyte chemoattractant protein 1 receptor, MCP-1-R, MCP-1R |
| 克隆号 | REA624 |
| 同种亚型 | recombinant human IgG1 |
