Anti-PTK7 (CCK-4)-Biotin, human 30 tests
货号：
130-100-176 基本售价：
询价 规格：
30 tests
产品信息
概述| 货号 | 130-100-176 |
| 描述 | The Anti-PTK7 (CCK-4) antibody (clone 188B) recognizes human protein tyrosine kinase-7 (PTK7). PTK7, also known as colon carcinoma kinase-4 (CCK-4), is a receptor protein tyrosine kinase (RPTK)-like molecule that contains a catalytically inactive tyrosine kinase domain.1,2 PTK7 was identified to be important for neural development as a regulator of planar cell polarity, being required for convergent extension movement and neural tube closure.3 Using the Anti-PTK7 (CCK-4) antibody, PTK7 expression was recently analyzed on blood and bone marrow cells. PTK7 was shown to be expressed on plasmacytoid dendritic cells, CD141 (BDCA-3)high type-2 myeloid dendritic cells, and CD34+ hematopoietic progenitor cells (HPCs). PTK7 was detected on early (CD34+CD133+) and late (CD34+CD133–) HPCs. In tonsils, PTK7 was also found on some T cells. |
| 别名 | CCK-4, CCK4 |
| 克隆号 | 188B |
| 同种亚型 | mouse IgG2aκ |
