CD209 (DC-SIGN)-FITC, human 30 tests
货号：
130-100-086 基本售价：
询价 规格：
30 tests
产品信息
概述| 货号 | 130-100-086 |
| 描述 | Clone DCN47.5 recognizes CD209 (Dendritic Cell Specific ICAM-3 Grabbing Non-integrin, DC-SIGN), a type II c-type lectin expressed in dermal and mucous tissue, lymphoid tissue such as tonsil, lymph node, spleen, and on monocyte-derived DCs (MoDCs). It is not expressed on DC subsets in peripheral blood, except for a subpopulation of CD14+ cells with a DC-like phenotype.DC-SIGN acts as an adhesion receptor to facilitate interactions between DCs and T cells or DCs and endothelial cells. In addition, it serves as an antigen receptor mediating internalization of ligands for antigen presentation, binding virus such as HIV, HCMV, or Ebola as well as parasites, bacteria, or yeast.HIV-1 uses this feature of DC-SIGN for efficient in -trans infection of CD4+ T cells. |
| 别名 | CDSIGN, CLEC4L, DC-SIGN |
| 克隆号 | DCN47.5 |
| 同种亚型 | mouse IgG1κ |
