CD283-FITC, human 30 tests
货号：
130-100-001 基本售价：
询价 规格：
30 tests
产品信息
概述| 货号 | 130-100-001 |
| 描述 | The monoclonal antibody TLR 3.7 reacts with CD283, also known as toll-like receptor 3 (TLR3). Toll-like receptors are a family of pattern recognition receptors that have evolved to detect components of foreign pathogens referred to as pathogenassociated molecular patterns. TLR3 is a single-pass type I membrane protein expressed exclusively in intracellular vesicles, such as the endoplasmic reticulum (ER), endosomes, lysosomes, and endolysosomes, where it recognizes microbial dsRNA. Multiple cell types are known to express TLR3 including dendritic cells, keratinocytes, and neurons. TLR3 activates via the TRIF-dependent pathway antiviral immune responses through the production of type I interferon and inflammatory cytokines, suggesting that TLR3 has an essential role in the prevention of viral infection. |
| 别名 | TLR3, IIAE2 |
| 克隆号 | TLR 3.7 |
| 同种亚型 | mouse IgG1κ |
