Anti-IgE-FITC, human 30 tests
货号：
130-099-376 基本售价：
询价 规格：
30 tests
产品信息
概述| 货号 | 130-099-376 |
| 描述 | Anti-IgE antibodies react with the IgE isotype of human immunoglobulins. IgE is the shortest-lived immunoglobulin with a half-life of two days in serum. IgE plays an important role in allergy. It is especially associated with type 1 hypersensitivity, where IgE shows high-affinity binding to Fc receptors expressed on the surface of mast cells. Antigen binding to Fc receptor–bound IgE upon re-exposure to specific allergens results in degranulation and the release of a variety of mediators, such as histamine and cytokines.IgE has two main receptors: the high-affinity receptor FcεRI, which is expressed only on mast cells and basophils, and the low-affinity receptor FcεRII (CD23), which is expressed on B cells. |
| 别名 | IGHE |
| 克隆号 | MB10-5C4 |
| 同种亚型 | mouse IgG1κ |
