CD338 (ABCG2)-Biotin, human 30 tests
货号：
130-105-008 基本售价：
询价 规格：
30 tests
产品信息
概述| 货号 | 130-105-008 |
| 描述 | Clone 5D3 recognizes the human CD338 antigen, a multi-pass membrane protein which is also known as ATP-binding cassette sub-family G member 2 (ABCG2) or breast cancer resistance protein (BCRP). CD338 is a member of the ATP-binding cassette transporter superfamily and is known to contribute to multidrug resistance in cancer chemotherapy. It is highly expressed on primitive stem cells as identified by the side-population phenotype, which is characterized by the efflux of chemicals, including the fluorescent dye Hoechst 33342 and Rhodamine 123. Among ABC transporters that are known to cause multidrug resistance, CD338 is particularly interesting for its potential role in protecting cancer stem cells and its complex oligomeric structure. |
| 别名 | ABCG2, Breast cancer resistance protein (BCRP, BCRP1), CDw338, Mitoxantrone resistance-associated protein (MXR), Placenta-specific ATP-binding cassette transporter, Urate exporter |
| 克隆号 | 5D3 |
| 同种亚型 | mouse IgG2bκ |
