CD328 (Siglec-7)-Biotin, human 30 tests
货号：
130-101-002 基本售价：
询价 规格：
30 tests
产品信息
概述| 货号 | 130-101-002 |
| 描述 | Clone REA214 recognizes CD328, which is a member of Sialic acid-binding immunoglobulin-like lectins (Siglecs) family of trans-membrane proteins. Upon recognizing their natural ligands, the sialylated carbohydrates, Siglecs generally transmit an inhibitory signal. CD328 is a 75 kDa type I trans-membrane protein and further belongs to the human CD33-related Siglec receptors with sialic acid binding N-terminal Ig domain, two C2-set Ig domains, and a cytoplasmic region containing one immune-receptor tyrosine based inhibitory motif (ITIM) and one ITIM-like motif. Expression of CD328 is found on natural killer (NK) cells, monocytes, and on a small subset of CD8+/CD3+ T cells and it preferentially binds (2,8)-linked disialic acids and branched 2,6-sialyl residues. Additional information: Clone REA214 displays negligible binding to Fc receptors. |
| 别名 | AIRM1, CDw328, D-siglec, QA79, Siglec-7, SIGLEC19P, SIGLECP2, p75, p75/AIRM1 |
| 克隆号 | REA214 |
| 同种亚型 | recombinant human IgG1 |
