CD270 (HVEM)-Biotin, human 30 tests
货号：
130-101-622 基本售价：
询价 规格：
30 tests
产品信息
概述| 货号 | 130-101-622 |
| 描述 | Clone REA247 recognizes CD270, which is also known as HVEM and derives its name based on the ability of types 1 and 2 herpesvirus gD to bind to it for entry into the cell. CD270 is a type 1 transmembrane protein with a predicted molecular weight of 30 kDa and is a member of TNFR superfamily. CD270 transmits both activating and inhibitory signals for, e.g., interaction with receptors such as BTLA or CD160 attenuates TCR-mediated signaling, whereas interaction with receptor LIGHT allows co-stimulation of T and B cells. Expression of CD270 is widely distributed and is found on hematopoietic cells such as dendritic cells, Tregs, monocytes, neutrophils, NK cells, B cells, and T cells, as well as on non-hematopoietic cells. Additional information: Clone REA247 displays negligible binding to Fc receptors. |
| 别名 | TNFRSF14, ATAR, HVEA, HVEM, LIGHTR, TR2 |
| 克隆号 | REA247 |
| 同种亚型 | recombinant human IgG1 |
