CD197 (CCR7)-FITC, human 30 tests
货号：
130-099-174 基本售价：
询价 规格：
30 tests
产品信息
概述| 货号 | 130-099-174 |
| 描述 | REA108 recognizes human CD197 which is a chemokine receptor with a C-C motif that mediates homing of T cells to secondary lymphoid organs via high endothelial venules (HEV) and is also known as CCR7. For example, naive T cells migrate very efficiently through lymph nodes using the adhesion molecules L-selectin, CD62L, and CCR7. Ligands for CCR7, e.g. CCL19, are expressed by the HEV of secondary lymphoid organs, by parenchymal cells within T cell zones of lymph nodes, and by endothelial cells at the openings of lymphatic vessels within peripheral tissues. Expression of CCR7 and the CD45RA isoform distinguishes three subsets of T cells: naive T cells (CCR7+CD45RA+), central memory T cells (CCR7+CD45RA–), and effector memory T cells (CCR7–CD45RA–).Additional information: Clone REA108 displays negligible binding to Fc receptors. |
| 别名 | CCR7, BLR-2, CC-CKR-7, CCR-7, Cdw197, CMKBR7, EBI-1 |
| 克隆号 | REA108 |
| 同种亚型 | recombinant human IgG1 |
