CD183 (CXCR3)-Biotin, human 30 tests
货号：
130-106-179 基本售价：
询价 规格：
30 tests
产品信息
概述| 货号 | 130-106-179 |
| 描述 | Clone REA232 recognizes CD183, a 38 kDa G protein–coupled chemokine receptor. CD183 harbors seven-transmembrane α-helices, an extracellular N-terminal domain containing three loops involved in the chemokine ligand binding, an intracellular C-terminal domain involved in signal transduction. CD183 binds CXCL9, CXCL10, and CXCL11 as ligands. CD183-ligand interactions play role in diverse cellular functions such as chemotactic migration, cell proliferation, and death. Expression of CD183 is found on T cells, human airway epithelial cells, NK cells, plasmacytoid dendritic cells, mast cells, alveolar macrophages, and eosinophils. Additional information: Clone REA232 displays negligible binding to Fc receptors. |
| 别名 | CXCR3, CD183, CKR-L2, CMKAR3, GPR9, IP10-R, Mig-R, MigR |
| 克隆号 | REA232 |
| 同种亚型 | recombinant human IgG1 |
