CD182 (CXCR2)-Biotin, human 30 tests
货号:
130-100-922 基本售价:
询价 规格:
30 tests
产品信息
概述货号 | 130-100-922 |
描述 | Clone REA208 recognizes CD182 (CXCR2), which belongs to the class of chemokine receptors specific for CXC chemokines. Chemokine receptors are G-coupled protein receptors (GPCR) with seven-transmembrane domains and consist of an α-subunit and a βγ-complex. In humans, IL-8 is one of most potent chemokine which binds to CXCR2. Expression of CD182 is found on several cell types including leukocytes, endothelial, and epithelial cells. CD182 plays a critical role in neutrophil homeostatis, angiogenesis, and in pathological conditions such as acute lung injury, lung diseases, and asthma. Additional information: Clone REA208 displays negligible binding to Fc receptors. |
别名 | CXCR2, CDw128b, CMKAR2, IL8R2, IL8RA, CD128b, IL-8RB |
克隆号 | REA208 |
同种亚型 | recombinant human IgG1 |