CD181 (CXCR1)-FITC, human 30 tests
货号：
130-105-392 基本售价：
询价 规格：
30 tests
产品信息
概述| 货号 | 130-105-392 |
| 描述 | Clone 8F1 recognizes the human CD181 antigen, a multi-pass membrane protein also known as C-X-C chemokine receptor type 1 (CXCR1) or IL-8 receptor A (IL-8RA). CD181 is expressed as homodimer or heterodimer with CD182 (CXCR2) and found on granulocytes, NK cells, a subset of T lymphocytes, mast cells, monocytes, endothelial cells, megakarocytes, and oligodendrocytes. It is one of two high-affinity receptors for IL-8, a major mediator of immune and inflammatory responses implicated in many disorders, including tumor growth. IL-8, released in response to inflammatory stimuli, binds to the extracellular part of CD181. The ligand-activated intracellular signaling pathways results in neutrophil migration to the site of inflammation. |
| 别名 | CXCR1, C-C, C-C-CKR-1, CDw128a, CKR-1, CMKAR1, IL8R1, IL8RA, IL8RBA |
| 克隆号 | 8F1 |
| 同种亚型 | mouse IgG2bκ |
