CD18-FITC, human 30 tests
货号：
130-101-242 基本售价：
询价 规格：
30 tests
产品信息
概述| 货号 | 130-101-242 |
| 描述 | Clone TS1/18 reacts with CD18, a type I transmembrane protein with an approximate molecular weight of 90–95 kDa. It non-covalently associates with α subunits CD11a (αL), CD11b (αM), CD11c (αX), and CD11d (αD) to form functional integrins which are expressed on leucocytes. CD18 associated integrins bind several ligands including cell surface and extracellular matrix proteins and are involved in cell-cell and cell-extracellular matrix interactions, immune regulation, and immune tolerance. Leucocytes of patients lacking CD18 or expressing dysfunctional CD18 are defective in chemotaxis, phagocytosis, and homotypic aggregation. |
| 别名 | ITGB2, CD18, LAD, LCAMB, LFA-1, Mac-1 α, MF17, MFI7 |
| 克隆号 | TS1/18 |
| 同种亚型 | mouse IgG1κ |
