CD177-FITC, human 30 tests
货号：
130-101-521 基本售价：
询价 规格：
30 tests
产品信息
概述| 货号 | 130-101-521 |
| 描述 | Clone REA258 recognizes CD177, which is also known as neutrophil specific antigen 1. CD177, a member of the µPAR family is a 58- to 64-kDa glycosylphosphatidylinositol-anchored glycoprotein expressed exclusively by subset of neutrophils, neutrophilic metamyelocytes, and myelocytes. CD177 is suggested to play a role in neutrophil mediated immune reponse as evident by its up-regulation on neutrophils in a number of inflammatory settings such as bacterial infection. Furthermore, CD177 can directly bind to PECAM-1 allowing neutrophil-endothelial cell interactions and thus contributing to neutrophil transmigration. Overexpression of CD177 is also seen in patients with polycythemia vera, making it a useful diagnostic marker. Additional Information: Clone REA258 displays negligible binding to Fc receptors. |
| 别名 | HNA-2a, NB1, NB1 GP, PRV-1, PRV1 |
| 克隆号 | REA258 |
| 同种亚型 | recombinant human IgG1 |
