CD158b2 (KIR2DL3)-FITC, human 30 tests
货号：
130-100-124 基本售价：
询价 规格：
30 tests
产品信息
概述| 货号 | 130-100-124 |
| 描述 | Clone REA147 recognizes CD158b2, a killer-cell immunoglobulin-like inhibitory receptor (KIR). Expressed by natural killer and a subset of T cells, KIR family of receptors are transmembrane glycoproteins and interact with MHC class I molecules. This interaction allows the KIR receptors to modulate the killing function of cells bearing them. The KIR proteins are categorized by the number of extracellular immunoglobulin domains (2D or 3D) and by the length (long (L) or short (S)) of the cytoplasmic domain. KIR proteins with the long cytoplasmic domain, such as CD158b2, transduce inhibitory signals via an immune tyrosine-based inhibitory motif (ITIM).Additional Information: Clone REA147 displays negligible binding to Fc receptors. |
| 别名 | KIR2DL3, Killer cell immunoglobulin-like receptor 2DL3 |
| 克隆号 | REA147 |
| 同种亚型 | recombinant human IgG1 |
