CD158a (KIR2DL1)-Biotin, human 30 tests
货号：
130-103-965 基本售价：
询价 规格：
30 tests
产品信息
概述| 货号 | 130-103-965 |
| 描述 | Clone REA284 recognizes human CD158a (KIR2DL1), but not KIR2DL2, 2DL3, 2DL4, 2DL5, 2DS1, 2DS2, 2DS4, 3DL1, 3DL2, or 3DS1. CD158a is 58 kDa protein, also known as KIR2DL1. CD158a is a member of the family of killer cell immunoglobulin-like receptors (KIRs) comprising transmembrane glycoproteins expressed on NK cells and a subset of T cells. Many groups of KIRs exist including KIR3DL1-3, KIR3DS1, KIR2DL1-5, and KIR2DS1-5. The isoforms have either a short (S) or long (L) cytoplasmic domain which transduce either an activating or inhibitory signal, respectively. The ligands of CD158a (KIR2DL1) are HLA-C molecules with Asn77 and Lys80, but not Ser77 and Asn80. Additional information: Clone REA284 displays negligible binding to Fc receptors. |
| 别名 | KIR2DL1, KIR-K64, KIR221, NKAT, NKAT-1, p58.1 |
| 克隆号 | REA284 |
| 同种亚型 | recombinant human IgG1 |
