CD156c (ADAM10)-FITC, human 30 tests
货号：
130-104-424 基本售价：
询价 规格：
30 tests
产品信息
概述| 货号 | 130-104-424 |
| 描述 | Clone REA309 recognizes the human CD156c antigen, a Single-pass type I membrane protein which is also known as Disintegrin and metalloproteinase domain-containing protein 10 (ADAM10). CD156c belongs to the family of Disintegrin and Metalloproteinases (ADAMs) and is expressed ubiquitously on hematopoietic and non-hematopoietic cells. ADAMs have emerged as the major proteinase family that mediates proteolytic ectodomain release, a process known as "shedding". This shedding process has been recognised as a key mechanism for regulating the function of a diversity of cell surface proteins. Dysregulation of ectodomain shedding is associated with autoimmune and cardiovascular diseases, neurodegeneration, infection, inflammation and cancer. CD156c has been studied in the context of ectodomain shedding and has been demonstrated as key molecule in most of the shedding events in cancer and neurodegenerative disorders.Additional information: Clone REA309 displays negligible binding to Fc receptors. |
| 别名 | ADAM10, AD10, AD18, HsT18717, MADM, RAK, kuz |
| 克隆号 | REA309 |
| 同种亚型 | recombinant human IgG1 |
