CD11a-FITC, human 30 tests
货号：
130-105-478 基本售价：
询价 规格：
30 tests
产品信息
概述| 货号 | 130-105-478 |
| 描述 | Clone REA378 recognizes the human CD11a antigen, a single-pass type I membrane protein also known as integrin α-L (ITGAL). Integrins are heterodimeric adhesion molecules comprised of α- and β-subunits that participate in immune cell interactions as well as in immune cell-extracellular matrix interactions. CD11a combines with CD18 (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 is a receptor for CD54 (ICAM-1), CD102 (ICAM-2), CD50 (ICAM-3), and CD242 (ICAM-4). It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T cell–mediated killing, and antibody dependent killing by granulocytes and monocytes. Interactions between LFA-1 and CD54 (ICAM-1) play a critical role in T cell–B cell collaboration. Additional information: Clone REA378 displays negligible binding to Fc receptors. |
| 别名 | ITGAL, LFA-1, LFA1A, Leukocyte function-associated molecule 1 α chain |
| 克隆号 | REA378 |
| 同种亚型 | recombinant human IgG1 |
