CD116-Biotin, human 30 tests
货号：
130-100-997 基本售价：
询价 规格：
30 tests
产品信息
概述| 货号 | 130-100-997 |
| 描述 | Clone REA211 recognizes CD116, the α subunit of GM-CSF receptor, which serves as a receptor for GM-CSF cytokine. GM-CSF is involved in innate and adaptive immune responses to infection, stimuli such as presence of LPS, and inflammatory diseases, such as asthma, rheumatoid arthritis and multiple sclerosis. The GM-CSF receptor comprises of cytokine-specific α subunit, CD116, and βc subunit, which is a common subunit shared by interleukin-3 (IL-3), and IL-5. The human CD116 is a 378 residue glycoprotein with an extracellular N-terminal Ig-like domain, two fibronectin (FnIII) domains, and a 54 residue intracellular domain. Expression of CD116 is found on myeloid cells including monocytes, macrophages, neutrophils, eosinophils, dendritic cells, fibroblasts, endothelial cells and myeloid leukemias. Additional Information: Clone REA211 displays negligible binding to Fc receptors. |
| 别名 | CSF2RA, CSF2RA, GM-CSF-R-α |
| 克隆号 | REA211 |
| 同种亚型 | recombinant human IgG1 |
