CD106-Biotin, human 30 tests
货号：
130-104-161 基本售价：
询价 规格：
30 tests
产品信息
概述| 货号 | 130-104-161 |
| 描述 | Clone REA269 recognizes the CD106 antigen, a 110 kDa single chain type I glycoprotein, also known as vascular cell adhesion protein 1 (VCAM-1) or INCAM-100. CD106 is expressed on inflamed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflamed tissue. Upregulation of CD106 in endothelial cells by inflammatory stimuli and cytokines occurs as a result of increased gene transcription. Primarily, CD106 is an endothelial ligand for very late antigen-4 (VLA-4) or integrin α-4/β-7 and mediates both adhesion and signal transduction. The interactions play a pathophysiologic role in leukocyte adhesion, transmigration, and co-stimulation of T cell proliferation.Additional information: Clone REA269 displays negligible binding to Fc receptors. |
| 别名 | VCAM1, INCAM-100 |
| 克隆号 | REA269 |
| 同种亚型 | recombinant human IgG1 |
