Anti-TcRg/d-Biotin, human 30 tests
货号：
130-100-343 基本售价：
询价 规格：
30 tests
产品信息
概述| 货号 | 130-100-343 |
| 描述 | The T cell receptor is a heterodimeric glycoprotein associated with the CD3 antigen. The TCR consists of a α and a β chain (TCRα/β) or a γ and a δ chain (TCRγ/δ). Clone 11F2 reacts with a framework epitope of the γ/δ T cell–receptor. The γ and δ TCR chains are composed of constant and variable regions, each encoded by distinct gene segments. The γ chain forms either disulfide-linked or non-disulfide-linked heterodimers with the δ-subunit.The γ/δ Tcell–receptor is present on a subset of T lymphocytes in peripheral blood, intestinal epithelium, lymph node, thymus, and spleen. TCR γ/δ is involved in the recognition of certain bacterial, self-CD1 molecule, and tumor antigens bound to MHC class I. γ/δ T cells are mainly CD4 negative and CD8 negative. T cells expressing the γ/δ TCR have been shown to play a role in oral tolerance, innate immune response for some tumor cells, and autoimmune disease. Antigen presentation by γ/δ T cells has been reported. |
| 别名 | TRD, TCRD, TCRDV1, TRD@, TCRG, TRG@, TRG |
| 克隆号 | 11F2 |
| 同种亚型 | mouse IgG1κ |
