Anti-DCIR-Biotin, human 30 tests
货号：
130-105-028 基本售价：
询价 规格：
30 tests
产品信息
概述| 货号 | 130-105-028 |
| 描述 | Clone REA329 recognizes the human dendritic cell immunoreceptor (DCIR) antigen, a single-pass type II membrane protein with a single carbohydrate recognition domain which is also known as C-type lectin domain family 4 member A (CLEC4A) or lectin-like immunoreceptor (LLIR). DCIR is expressed on dendritic cells (DCs), monocytes, macrophages, B lymphocytes, and granulocytes, but not detected on NK and T cells. DCIR is strongly expressed by DC derived from blood monocytes cultured with GM-CSF and IL-4. It is mostly expressed by monocyte-related rather than Langerhans cell related DC obtained from CD34+ progenitor cells. Finally, DCIR expression is down-regulated by signals inducing DC maturation such as CD40 ligand, LPS, or TNF-α. Thus, DCIR is differentially expressed on DC depending on their origin and stage of maturation/activation. Additional information: Clone REA329 displays negligible binding to Fc receptors. |
| 别名 | CLEC4A, CD367, CLECSF6, DDB27, HDCGC13P, LLIR |
| 克隆号 | REA329 |
| 同种亚型 | recombinant human IgG1 |
