CD80-Biotin, human 30 tests
货号：
130-110-370 基本售价：
询价 规格：
EA
产品信息
概述| 货号 | 130-110-370 |
| 描述 | Clone REA661 recognizes the human CD80 antigen, also known as B7-1. CD80 is a 262 amino acid long 60 kDa molecule and a member of the immunoglobulin superfamily. Together with CD86 (B7-2) it belongs to the B7 family of costimulatory molecules. CD80 is expressed on activated B cells, dendritic cells, and monocytes/ macrophages. The interaction of CD80 with its ligands CD28 and CD152 (CTLA-4) plays a critical role in induction and regulation of immune responses. Binding of CD80 to CD28, which is constitutively expressed on T cells, provides a co-stimulatory signal and induces T cell proliferation and cytokine production. In contrast, binding to CTLA-4 strongly inhibits proliferation and IL-2 secretion by T cells.Additional Information: Clone REA661 displays negligible binding to Fc receptors. |
| 别名 | B7, B7-1, BB1 |
| 克隆号 | REA661 |
| 同种亚型 | recombinant human IgG1 |
