CD157 (BST-1)-Biotin, human 30 tests
货号：
130-106-980 基本售价：
询价 规格：
30 tests
产品信息
概述| 货号 | 130-106-980 |
| 描述 | Clone REA465 recognizes the human CD157 antigen, a glycosylphosphatidylinositol (GPI) linked protein, which is also known as bone marrow stromal antigen 1 (BST-1) or cyclic ADP-ribose hydrolase 2. CD157, a member of the CD38 gene family, is an NAD-metabolizing ectoenzyme and a signaling molecule, which synthesizes the second messengers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, former a second messenger that elicits calcium release from intracellular stores. It is mainly expressed by cells of the myeloid lineage, bone marrow stroma, and vascular endothelium. CD157 is also expressed by ovarian cancer epithelium and by peritoneal mesothelial cells, where it is implicated in tumor dissemination. Further, it is endowed with receptor-like features observed in different cell types and transduces signals by interacting with transmembrane partner molecules, a strategy shared by other GPI-anchored molecules. CD157 is involved in neutrophil polarization, adhesion, and motility and controls transendothelial migration.Additional information: Clone REA465 displays negligible binding to Fc receptors. |
| 别名 | BST-1 |
| 克隆号 | REA465 |
| 同种亚型 | recombinant human IgG1 |
