Anti-MPO-FITC, human 30 tests
货号：
130-107-177 基本售价：
询价 规格：
30 tests
产品信息
概述| 货号 | 130-107-177 |
| 描述 | Clone REA491 recognizes the human myeloperoxidase (MPO) antigen, a heterotetrameric protein consisting of two 15 kDa light chains and two variable-weight glycosylated heavy chains bound to a prosthetic heme group. MPO produces hypochlorous acid from hydrogen peroxide and chloride anion during the neutrophils respiratory burst. Furthermore, it oxidizes tyrosine to tyrosyl radical using hydrogen peroxide as an oxidizing agent. MPO is present in azurophilic granules of neutrophilic granulocytes and monocytes and is also expressed in some acute myeloid leukemia cells. It plays a major role in the oxygen-dependent microbicidal system of of polymorphonuclear leukocytes. The deficiency of this enzyme activity results in a marked microbicidal defect. Additional information: Clone REA491 displays negligible binding to Fc receptors. |
| 别名 | Myeloperoxidase |
| 克隆号 | REA491 |
| 同种亚型 | recombinant human IgG1 |
