Hu CD11b/Mac-1 APC ICRF44 100Tst
货号:
550019 基本售价:
4695.0 元 规格:
100Tst
产品信息
概述货号 | 550019 |
描述 | The ICRF44 monoclonal antibody specifically binds to CD11b, the 165-kDa adhesion glycoprotein that associates with the 95-kDa integrin β 2 (CD18) to form the CD11b/CD18 complex, also known as Mac-1 or CR3. CD11b is a type I transmembrane glycoprotein that is encoded by ITGAM (Integrin alpha M). It is expressed on activated lymphocytes, monocytes, granulocytes, and a subset of NK cells. CD11b functions in cell-cell and cell-substrate interactions and is a receptor for iC3b, CD54 (ICAM-1), CD102 (ICAM-2) and CD50 (ICAM-3). This antibody significantly inhibits polymorphonuclear leukocyte aggregation in response to fMLP. |
别名 | MAC-1A; Mac-1; ITGAM; Integrin alpha M; CR3A; CR-3 alpha; Mo1; SLEB6 |
同种亚型 | IgG1,κ |
反应种属 | Human (QC Testing) |
来源宿主 | Mouse |
使用方法 | FC |
性能供应商 | BD Pharmingen |
免疫原 | Human monocytes |
标记 | APC |
存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated to APC under optimum conditions, and unconjugated antibody and free APC were removed.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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存储溶液 | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |