Hu CD41b FITC HIP2 100Tst
货号:
555469 基本售价:
3388.0 元 规格:
100Tst
产品信息
概述货号 | 555469 |
描述 | The HIP2 monoclonal antibody specifically binds to CD41b. CD41b/CD41 is encoded by the ITGA2B gene and is also known as Platelet glycoprotein GPIIb and Integrin alpha IIb. CD41 is transmembrane glycoprotein that is post-translationally processed into a disulfide linked α-chain and β-chain. CD41 combines with CD61, otherwise known as Glycoprotein IIIa or β3 integrin, to form the CD41/CD61 (GPIIb/IIIa) complex. This complex is expressed on platelets and megakaryocytes and is involved in platelet activation, aggregation and binding to extracellular matrix proteins. Upon platelet activation, the CD41/CD61 complex can function as a receptor for fribrinogen, fibronectin and von Willebrand factor. In contrast to other CD41b antibodies, HIP2 does not detect anti-ZWa bound to GPIIb/IIIa. This antibody appears to be a weak aggregation inducer. |
别名 | ITGA2B; CD41; GP2B; GPIIb; GPalpha IIb; Platelet glycoprotein GPIIb |
同种亚型 | IgG3,κ |
反应种属 | Human (QC Testing) |
来源宿主 | Mouse |
使用方法 | FC |
性能供应商 | BD Pharmingen |
标记 | FITC |
存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with FITC under optimum conditions, and unreacted FITC was removed.
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存储溶液 | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |