Human Dkk-4 DuoSet ELISA, 15 Plate (1 KT)
货号：
DY1269 基本售价：
10120.7 元 规格：
1 KIT
产品信息
概述| 货号 | DY1269 |
| 别名 | dickkopf (Xenopus laevis) homolog 4; dickkopf homolog 4 (Xenopus laevis); dickkopf-4; dickkopf-related protein 4; Dkk4; Dkk-4; hDkk-4; MGC129562; MGC129563 |
全称 | Dickkopf-4 | | 反应种属 | Human |
| 目标/特异性 | Please see the product datasheet |
性能| 供应商 | R&D Systems |
| 检测类型 | Solid Phase Sandwich ELISA |
| Entrez Gene IDs | 27121 (Human); 234130 (Mouse); |
| 背景 | Members of the dickkopf-related protein family (Dkk-1, -2, -3, and -4) are secreted proteins with two cysteine-rich domains separated by a linker region. Dkk-3 and -4 also have one prokineticin domain. Dkk-1, -2, and -4 function as antagonists of canonical Wnt signaling by binding to LRP5/6, preventing interaction of LRP5/6 with Wnt-Frizzled complexes. Dkk-1, -2, and -4 also bind cell surface Kremen-1 or -2 and promote the internalization of LRP5/6. Antagonistic activity of Dkk-3 has not been demonstrated. Dkk proteins have distinct patterns of expression in adult and embryonic tissues and have a wide range of effects on tissue development and morphogenesis. The Dkk family also includes Soggy, which is homologous to Dkk-3 but not to the other family members. Soggy has not been shown to inhibit Wnt signaling, and its role in the pathway is unclear. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
