| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Cessation of CCL2 inhibition accelerates breast cancer metastasis by promoting angiogenesis.
Authors: Bonapace L, Coissieux M, Wyckoff J, Mertz K, Varga Z, Junt T, Bentires-Alj M
Nature, 2015;515(7525):130-3.
Species: Mouse
Sample Type: Cell Culture Supernates
Autoprocessing of neutrophil elastase near its active site reduces the efficiency of natural and synthetic elastase inhibitors.
Authors: Dau T, Sarker R, Yildirim A, Eickelberg O, Jenne D
Nat Commun, 2015;6(0):6722.
Species: Mouse
Sample Type: BALF
IL-1 receptor type 2 suppresses collagen-induced arthritis by inhibiting IL-1 signal on macrophages.
Authors: Shimizu K, Nakajima A, Sudo K, Liu Y, Mizoroki A, Ikarashi T, Horai R, Kakuta S, Watanabe T, Iwakura Y
J Immunol, 2015;194(7):3156-68.
Species: Mouse
Sample Type: Cell Culture Supernates
A TNF-alpha-CCL20-CCR6 axis regulates Nod1-induced B cell responses.
Authors: Paradis M, Mindt B, Duerr C, Rojas O, Ng D, Boulianne B, McCarthy D, Yu M, Summers deLuca L, Ward L, Waldron J, Philpott D, Gommerman J, Fritz J
J Immunol, 2014;192(6):2787-99.
Species: Mouse
Sample Type: Serum
Bone marrow-specific knock-in of a non-activatable Ikkalpha kinase mutant influences haematopoiesis but not atherosclerosis in Apoe-deficient mice.
Authors: Tilstam P, Gijbels M, Habbeddine M, Cudejko C, Asare Y, Theelen W, Zhou B, Doring Y, Drechsler M, Pawig L, Simsekyilmaz S, Koenen R, de Winther M, Lawrence T, Bernhagen J, Zernecke A, Weber C, Noels H
PLoS ONE, 2014;9(2):e87452.
Species: Mouse
Sample Type: Cell Culture Supernates
Circadian clock function is disrupted by environmental tobacco/cigarette smoke, leading to lung inflammation and injury via a SIRT1-BMAL1 pathway.
Authors: Hwang J, Sundar I, Yao H, Sellix M, Rahman I
FASEB J, 2014;28(1):176-94.
Species: Mouse
Sample Type: Tissue Homogenates
Modulation of the mevalonate pathway by akt regulates macrophage survival and development of pulmonary fibrosis.
Authors: Larson-Casey J, Murthy S, Ryan A, Carter A
J Biol Chem, 2014;289(52):36204-19.
Species: Mouse
Sample Type: BALF
Munc18-2 and syntaxin 3 control distinct essential steps in mast cell degranulation.
Authors: Brochetta C, Suzuki R, Vita F, Soranzo M, Claver J, Madjene L, Attout T, Vitte J, Varin-Blank N, Zabucchi G, Rivera J, Blank U
J Immunol, 2014;192(1):41-51.
Species: Rat
Sample Type: Cell Culture Supernates
A2B adenosine receptors prevent insulin resistance by inhibiting adipose tissue inflammation via maintaining alternative macrophage activation.
Authors: Csoka B, Koscso B, Toro G, Kokai E, Virag L, Nemeth Z, Pacher P, Bai P, Hasko G
Diabetes, 2014;63(3):850-66.
Species: Mouse
Sample Type: Plasma
Hypothalamic gene transfer of BDNF inhibits breast cancer progression and metastasis in middle age obese mice.
Authors: Liu, Xianglan, McMurphy, Travis, Xiao, Run, Slater, Andrew, Huang, Wei, Cao, Lei
Mol Ther, 2014;22(7):1275-84.
Species: Mouse
Sample Type: Serum
The role of Nox2-derived ROS in the development of cognitive impairment after sepsis.
Authors: Hernandes M, DAvila J, Trevelin S, Reis P, Kinjo E, Lopes L, Castro-Faria-Neto H, Cunha F, Britto L, Bozza F
J Neuroinflammation, 2014;11(0):36.
Species: Mouse
Sample Type: Peritoneal Fluid
MicroRNA-155 is essential for T(H)2-mediated allergen-induced eosinophilic inflammation in the lung.
Authors: Malmhall C, Alawieh S, Lu Y, Sjostrand M, Bossios A, Eldh M, Radinger M
J Allergy Clin Immunol, 2014;133(5):1429-38, 1438.
Species: Mouse
Sample Type: Tissue Homogenates
Defining the range of pathogens susceptible to Ifitm3 restriction using a knockout mouse model.
Authors: Everitt, Aaron R, Clare, Simon, McDonald, Jacqueli, Kane, Leanne, Harcourt, Katherin, Ahras, Malika, Lall, Amar, Hale, Christin, Rodgers, Angela, Young, Douglas, Haque, Ashraful, Billker, Oliver, Tregoning, John S, Dougan, Gordon, Kellam, Paul
PLoS ONE, 2013;8(11):e80723.
Species: Mouse
Sample Type: BALF
Syntaxin binding protein 1 is not required for allergic inflammation via IgE-mediated mast cell activation.
Authors: Wu Z, MacNeil A, Berman J, Lin T
PLoS ONE, 2013;8(3):e58560.
Species: Mouse
Sample Type: cell supernates
Effect of secretin on preadipocyte, differentiating and mature adipocyte functions.
Authors: Miegueu P, Cianflone K, Richard D, St-Pierre D
Int J Obes (Lond), 2013;37(3):366-74.
Species: Mouse
Sample Type: cell supernates
Role of Toll interleukin-1 receptor (IL-1R) 8, a negative regulator of IL-1R/Toll-like receptor signaling, in resistance to acute Pseudomonas aeruginosa lung infection.
Authors: Veliz Rodriguez T, Moalli F, Polentarutti N, Paroni M, Bonavita E, Anselmo A, Nebuloni M, Mantero S, Jaillon S, Bragonzi A, Mantovani A, Riva F, Garlanda C
Infect. Immun., 2012;80(1):100-9.
Species: Mouse
Sample Type: Serum
Suppression of cytokine storm with a sphingosine analog provides protection against pathogenic influenza virus.
Authors: Walsh KB, Teijaro JR, Wilker PR
Proc. Natl. Acad. Sci. U.S.A., 2011;108(29):12018-23.
Species: Mouse
Sample Type: BALF
Phosphoinositide 3-kinase gamma plays a critical role in bleomycin-induced pulmonary inflammation and fibrosis in mice.
Authors: Russo RC, Garcia CC, Barcelos LS, Rachid MA, Guabiraba R, Roffe E, Souza AL, Sousa LP, Mirolo M, Doni A, Cassali GD, Pinho V, Locati M, Teixeira MM
J. Leukoc. Biol., 2011;89(2):269-82.
Species: Mouse
Sample Type: Tissue Homogenates
The Therapeutic Potential of the Humoral Pattern Recognition Molecule PTX3 in Chronic Lung Infection Caused by Pseudomonas aeruginosa.
Authors: Moalli F, Paroni M, Veliz Rodriguez T, Riva F, Polentarutti N, Bottazzi B, Valentino S, Mantero S, Nebuloni M, Mantovani A, Bragonzi A, Garlanda C
J. Immunol., 2011;186(9):5425-34.
Species: Mouse
Sample Type: Tissue Homogenates
Lung-targeted overexpression of the NF-kappaB member RelB inhibits cigarette smoke-induced inflammation.
Authors: McMillan DH, Baglole CJ, Thatcher TH, Maggirwar S, Sime PJ, Phipps RP
Am. J. Pathol., 2011;179(1):125-33.
Species: Mouse
Sample Type: BALF
Inflammatory chemokine release of astrocytes in vitro is reduced by all-trans retinoic acid.
Authors: van Neerven S, Regen T, Wolf D, Nemes A, Johann S, Beyer C, Hanisch UK, Mey J
J. Neurochem., 2010;114(5):1511-26.
Species: Mouse
Sample Type: Cell Culture Supernates
Latent herpesvirus infection augments experimental pulmonary fibrosis.
Authors: Vannella KM, Luckhardt TR, Wilke CA, van Dyk LF, Toews GB, Moore BB
Am. J. Respir. Crit. Care Med., 2010;181(5):465-77.
Species: Mouse
Sample Type: Tissue Homogenates
Matrix metalloproteinase-9 deficiency worsens lung injury in a model of bronchopulmonary dysplasia.
Authors: Lukkarinen H, Hogmalm A, Lappalainen U, Bry K
Am. J. Respir. Cell Mol. Biol., 2009;41(1):59-68.
Species: Mouse
Sample Type: Tissue Homogenates
Reduction in dietary omega-6 polyunsaturated fatty acids: eicosapentaenoic acid plus docosahexaenoic acid ratio minimizes atherosclerotic lesion formation and inflammatory response in the LDL receptor null mouse.
Authors: Wang S, Wu D, Matthan NR, Lamon-Fava S, Lecker JL, Lichtenstein AH
Atherosclerosis, 2009;204(1):147-55.
Species: Mouse
Sample Type: Cell Culture Supernates
Oxidized alpha1-antitrypsin stimulates the release of monocyte chemotactic protein-1 from lung epithelial cells: potential role in emphysema.
Authors: Li Z, Alam S, Wang J, Sandstrom CS, Janciauskiene S, Mahadeva R
Am. J. Physiol. Lung Cell Mol. Physiol., 2009;297(2):L388-400.
Species: Mouse
Sample Type: BALF
Modulation of macrophage infiltration and inflammatory activity by the phosphatase SHP-1 in virus-induced demyelinating disease.
Authors: Christophi GP, Hudson CA, Panos M, Gruber RC, Massa PT
J. Virol., 2009;83(2):522-39.
Species: Mouse
Sample Type: Cell Culture Supernates
E-prostanoid 3 receptor deletion improves pulmonary host defense and protects mice from death in severe Streptococcus pneumoniae infection.
Authors: Aronoff DM, Lewis C, Serezani CH, Eaton KA, Goel D, Phipps JC, Peters-Golden M, Mancuso P
J. Immunol., 2009;183(4):2642-9.
Species: Mouse
Sample Type: Tissue Homogenates
Neurokinin A engages neurokinin-1 receptor to induce NF-kappaB-dependent gene expression in murine macrophages: implications of ERK1/2 and PI 3-kinase/Akt pathways.
Authors: Sun J, Ramnath RD, Tamizhselvi R, Bhatia M
Am. J. Physiol., Cell Physiol., 2008;295(3):C679-91.
Species: Mouse
Sample Type: Cell Culture Supernates
Central role of MyD88-dependent dendritic cell maturation and proinflammatory cytokine production to control Brucella abortus infection.
Authors: Macedo GC, Magnani DM, Carvalho NB, Bruna-Romero O, Gazzinelli RT, Oliveira SC
J. Immunol., 2008;180(2):1080-7.
Species: Mouse
Sample Type: Cell Culture Supernates
Distinct roles for IL-13 and IL-4 via IL-13 receptor alpha1 and the type II IL-4 receptor in asthma pathogenesis.
Authors: Munitz A, Brandt EB, Mingler M, Finkelman FD, Rothenberg ME
Proc. Natl. Acad. Sci. U.S.A., 2008;105(20):7240-5.
Species: Mouse
Sample Type: BALF
Expanded-polyglutamine huntingtin protein suppresses the secretion and production of a chemokine (CCL5/RANTES) by astrocytes.
Authors: Chou SY, Weng JY, Lai HL, Liao F, Sun SH, Tu PH, Dickson DW, Chern Y
J. Neurosci., 2008;28(13):3277-90.
Species: Mouse
Sample Type: Cell Culture Supernates
Scavenging roles of chemokine receptors: chemokine receptor deficiency is associated with increased levels of ligand in circulation and tissues.
Authors: Cardona AE, Sasse ME, Liu L, Cardona SM, Mizutani M, Savarin C, Hu T, Ransohoff RM
Blood, 2008;112(2):256-63.
Species: Mouse
Sample Type: Tissue Homogenates
Surfactant protein D alters allergic lung responses in mice and human subjects.
Authors: Brandt EB, Mingler MK, Stevenson MD, Wang N, Khurana Hershey GK, Whitsett JA, Rothenberg ME
J. Allergy Clin. Immunol., 2008;121(5):1140-1147.e2.
Species: Mouse
Sample Type: BALF
Osteopontin regulates hindlimb-unloading-induced lymphoid organ atrophy and weight loss by modulating corticosteroid production.
Authors: Wang KX, Shi Y, Denhardt DT
Proc. Natl. Acad. Sci. U.S.A., 2007;104(37):14777-82.
Species: Mouse
Sample Type: Cell Culture Supernates
Infiltrating neutrophils induce allospecific CTL in response to immunization with apoptotic cells via MCP-1 production.
Authors: Shiratsuchi Y, Iyoda T, Tanimoto N, Kegai D, Nagata K, Kobayashi Y
J. Leukoc. Biol., 2007;81(2):412-20.
Species: Mouse
Sample Type: Peritoneal Lavage
CD8+ T Cells are required for inflammation and destruction in cigarette smoke-induced emphysema in mice.
Authors: Maeno T, Houghton AM, Quintero PA, Grumelli S, Owen CA, Shapiro SD
J. Immunol., 2007;178(12):8090-6.
Species: Mouse
Sample Type: BALF
Dual effect of AMD3100, a CXCR4 antagonist, on bleomycin-induced lung inflammation.
Authors: Watanabe M, Matsuyama W, Shirahama Y, Mitsuyama H, Oonakahara K, Noma S, Higashimoto I, Osame M, Arimura K
J. Immunol., 2007;178(9):5888-98.
Species: Mouse
Sample Type: Tissue Homogenates
Nod1-mediated innate immune recognition of peptidoglycan contributes to the onset of adaptive immunity.
Authors: Fritz JH, Le Bourhis L, Sellge G, Magalhaes JG, Fsihi H, Kufer TA, Collins C, Viala J, Ferrero RL, Girardin SE, Philpott DJ
Immunity, 2007;26(4):445-59.
Species: Mouse
Sample Type: Cell Culture Supernates
Neurokinin-1 receptor antagonist treatment protects mice against lung injury in polymicrobial sepsis.
Authors: Hegde A, Zhang H, Moochhala SM, Bhatia M
J. Leukoc. Biol., 2007;82(3):678-85.
Species: Mouse
Sample Type: Plasma
Mycobacterium tuberculosis antigens specifically modulate CCR2 and MCP-1/CCL2 on lymphoid cells from human pulmonary hilar lymph nodes.
Authors: Arias MA, Jaramillo G, Lopez YP, Mejia N, Mejia C, Pantoja AE, Shattock RJ, Garcia LF, Griffin GE
J. Immunol., 2007;179(12):8381-91.
Species: Human
Sample Type: Cell Culture Supernates
Increased pulmonary responses to acute ozone exposure in obese db/db mice.
Authors: Lu FL, Johnston RA, Flynt L, Theman TA, Terry RD, Schwartzman IN, Lee A, Shore SA
Am. J. Physiol. Lung Cell Mol. Physiol., 2006;290(5):L856-65.
Species: Mouse
Sample Type: Serum
Exogenous platelet-activating factor acetylhydrolase reduces mortality in mice with systemic inflammatory response syndrome and sepsis.
Authors: Gomes RN, Bozza FA, Amancio RT, Japiassu AM, Vianna RC, Larangeira AP, Gouvea JM, Bastos MS, Zimmerman GA, Stafforini DM, Prescott SM, Bozza PT, Castro-Faria-Neto HC
Shock, 2006;26(1):41-9.
Species: Mouse
Sample Type: Peritoneal Fluid
A functional comparison of canine and murine bone marrow derived cultured mast cells.
Authors: Lin TY, London CA,
Vet. Immunol. Immunopathol., 2006;114(3):320-34.
Species: Mouse
Sample Type: Cell Culture Supernates
Differential involvement of TLR2 and TLR4 in host survival during pulmonary infection with Chlamydia pneumoniae.
Authors: Rodriguez N, Wantia N, Fend F, Durr S, Wagner H, Miethke T
Eur. J. Immunol., 2006;36(5):1145-55.
Species: Mouse
Sample Type: Tissue Homogenates
Impaired inflammatory angiogenesis, but not leukocyte influx, in mice lacking TNFR1.
Authors: Barcelos LS, Talvani A, Teixeira AS, Vieira LQ, Cassali GD, Andrade SP, Teixeira MM
J. Leukoc. Biol., 2005;78(2):352-8.
Species: Mouse
Sample Type: sponge fluids
Immunosuppressive effects of CCL17 on pulmonary antifungal responses during pulmonary invasive aspergillosis.
Authors: Carpenter KJ, Hogaboam CM
Infect. Immun., 2005;73(11):7198-207.
Species: Mouse
Sample Type: Tissue Homogenates
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