货号 | 2005S |
反应种属 | Human/Mouse |
来源宿主 | Rabbit |
应用 | W/IP/IHC-P/IF-IC/F |
目标/特异性 | FoxP1 Antibody detects endogenous level of total FoxP1 protein. |
使用方法 | WB(1:1000) IP (1:50) IHC-P (1:400) F (1:200) IF-IC (1:400) |
供应商 | CST |
背景 | Forkhead box (Fox) proteins are a family of evolutionarily conserved transcription factors containing a sequence known as Forkhead box or winged helix DNA binding domain (1). The human genome contains 43 Fox proteins that are divided into subfamilies. The FoxP subfamily has four members, FoxP1 to FoxP4, which are broadly expressed and play important roles in organ development, immune response, and cancer pathogenesis (2-4). The FoxP subfamily has several characteristics that are atypical among Fox proteins: their Forkhead domain is located at the carboxy-terminal region, and they contain motifs that promote homo- and heterodimerization. FoxP proteins usually function as transcriptional repressors (4,5). |
存放说明 | -20C |
计算分子量 | 82-90 |
Western blot analysis of extracts from HBP-ALL cells, HCT-15 cells and mouse thymocytes using FoxP1 Antibody. 使用FoxP1抗体对HBP-ALL细胞,HCT-15和小鼠胸腺细胞提取物进行western blot分析。 | |
Immunohistochemical analysis of paraffin-embedded human tonsil epithelium using FoxP1 Antibody in the presence of control peptide (left) or antigen-specific peptide (right). 在对照肽段(左)或抗原特异性多肽(右)存在的条件下,使用FoxP1抗体对石蜡包埋的人扁桃腺上皮组织进行免疫组化分析。 | |
Flow cytometric analysis of MCF-7 cells using FoxP1 Antibody (blue) compared to a nonspecific negative control antibody (red). 使用FoxP1抗体(蓝色)对MCF-7进行流式细胞分析,非特异抗体作为阴性对照(红色)。 | |
Confocal immunofluorescent analysis of MCF-7 cells using FoxP1 Antibody (green). Actin filaments have been labeled using DY-554 phalloidin (red). 使用FoxP1抗体(绿色)对MCF-7细胞进行激光共聚焦荧光分析。肌动蛋白丝使用DY-554 phalloidin 标记(红色)。 | |
Immunohistochemical analysis of paraffin-embedded human lymphoma using FoxP1 Antibody. 使用FoxP1抗体对石蜡包埋的人淋巴瘤进行免疫组化分析。 | |
Immunohistochemical analysis of paraffin-embedded human lung carcinoma using FoxP1 Antibody. 使用FoxP1抗体对石蜡包埋的人肺癌组织进行免疫组化分析。 |