Anti-IRF4-PE-Vio770, h&m 30 tests
货号：
130-100-877 基本售价：
询价 规格：
30 tests
产品信息
概述| 货号 | 130-100-877 |
| 描述 | Clone REA201 recognizes IRF-4, which is a 52 KDa transcription factor and belongs to the family of interferon regulatory transcription factors.The IRF family consists of nine members in both human and mice and is characterised by a conserved N-terminal DNA-binding domain (DBD) with unique tryptophan pentad repeat and modulates the expression of genes regulated by the presence of interferons and in response to cell activation. Expression of IRF4 is found in cells of the immune system, including lymphocytes, dendritic cells and macrophages, where its multiple functions include regulation of cell proliferation, apoptosis and differentiation. Transcriptional activity of IRF4 is further modulated by its interaction with various co-factors including including Pu.1, E47, STAT-6 and IRF8.Additional Information: Clone REA201 displays negligible binding to Fc receptors. |
| 别名 | IRF4, LSIRF, MUM1, NF-EM5, SHEP8, LSIRF, Spip, LSIRF13, ICSAT14 |
| 克隆号 | REA201 |
| 同种亚型 | recombinant human IgG1 |
