Anti-SHIP-1-PE, human, mouse 30 tests
货号:
130-109-201 基本售价:
询价 规格:
30 tests
产品信息
概述货号 | 130-109-201 |
描述 | Clone REA580 recognizes the human and mouse SHIP-1 antigen, which is a 145 kDa protein with an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. SHIP-1, also known as enzyme phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1, is expressed on hematopoietic cells, including immature CD34+ cells, the majority of T cells, and a minority of B cells. It has a negative effect on cell growth and therefore loss or modification may have profound effects on hematopoietic cell development. Thus SHIP-1 functions as a negative regulator of myeloid cell proliferation and survival.Additional information: Clone REA580 displays negligible binding to Fc receptors. |
别名 | INPP5D, SHIP, SIP-145, hp51CN, p150Ship, SHIP1 |
克隆号 | REA580 |
同种亚型 | recombinant human IgG1 |